Umuti
Gutezimbere Gut Gut Microbiota
Uburyo bwo kuvura Gut Microbiota:
1. Guhindura Microbiota:
Harimo no gutera mikorobe yo munda kumuntu muzima kugirango agarure uburinganire bwa mikorobe ya nyirayo. Ubu buryo bukoreshwa cyane cyane mu kuvura indwara zifata gastrointestinal, enteritis, na syndrome de munda.
2.Guhindura Microbiota:
Harimo guhindura imiterere yimirire, ukoresheje probiotics cyangwa prebiotics, nubundi buryo bwo guhindura imiterere nimikorere ya microbiota yo munda. Ubu buryo bukoreshwa cyane cyane mukurinda no kuvura indwara nka dysbiose yo munda no kudakora neza.
Gutera mikorobe ya mikorobe yerekanye ibisubizo bitanga umusaruro mukuvura indwara zitandukanye, cyane cyane mubijyanye nindwara ziterwa na gastrointestinal hamwe nindwara ziterwa nubudahangarwa. Ubushakashatsi burimo gukorwa nubuvuzi burakenewe kugirango turusheho kwemeza imikorere yacyo no gukemura ibibazo bijyanye na tekiniki n’umutekano.
Gutera Microbiota Gutabara - Uburyo bushya bwo kuvura Autism:
Autism, indwara ya neurodevelopmental irangwa ningorane mu mibanire myiza, itumanaho ryindimi, nimyitwarire isubiramo, bifitanye isano nubuzima bwo munda. Muguhindura microbiota yo munda no kuzamura ubuzima bwinda, ingaruka nziza kubimenyetso bya autism irashobora kugerwaho. Iyi ngingo irasobanura akamaro k'ubuzima bwo munda mu kuvura autism.
Isano iri hagati yubuzima bwa Gut na Autism:
Abantu bafite autism bakunze guhura nibibazo byigifu nka diyare, impatwe, nibibazo byigifu. Ubushakashatsi bwerekanye itandukaniro muri microbiota yo munda yabantu bafite autism ugereranije nabatayifite. Ubusumbane muri microbiota burashobora guhagarika imikorere yinzitizi yo munda, bigatera ibisubizo bitera ingaruka kumikurire n'imikorere ya sisitemu y'imitsi. Kubwibyo, kuzamura ubuzima bwigifu byagaragaye nkuburyo bushya bwo kuvura autism.
Ishyirahamwe rya Probiotics hamwe na Autism:
Probiotics, mikorobe ngirakamaro iteza imbere ubuzima bwo munda, igira uruhare runini mugutunganya mikorobe ya mikorobe, kongera imikorere yinzitizi zo munda, no kugabanya uburibwe. Ubushakashatsi bwerekanye ko gukoresha porotiyotike bishobora gukemura ibibazo byo mu gifu ku bantu bafite autism, bikagira ingaruka nziza ku myitwarire yabo no mu mibanire yabo. Kurugero, ubushakashatsi bumwe bwerekanye ko gukoresha umunwa wa porotiyotike byatumye habaho iterambere ryimyitwarire mbonezamubano no kuvuga imvugo kubantu bafite autism.
Probiotics ninshuti nziza kubantu
Isano Hagati ya Gut Microbiota no Gutwika Ubwonko:
Gut microbiota igira uruhare runini mukubungabunga ubuzima bwabantu muri rusange, gufasha mu igogorwa ryibiryo, no gutanga intungamubiri zingenzi. Byongeye kandi, bigira ingaruka kumubiri kandi bigatanga imiti igira ingaruka kumikorere yubwonko. Uburinganire muri microbiota yo munda bushobora gutera indwara.
Byongeye kandi, amara microbiota arashobora no kugira ingaruka kubuzima bwubwonko. Ubushakashatsi bwerekana ko ubwonko na mikorobe yo mu nda bihujwe binyuze mu nda-ubwonko. Inda-ubwonko ni urusobe rugoye rugizwe na neuron, proteyine, nibintu bya shimi byorohereza itumanaho hagati yimikorere yubwonko n'ubwonko.
Isano iri hagati ya microbiota nindwara ya Alzheimer irahambaye cyane. Inda microbiota irashobora kugenga iterambere rya neuron binyuze muri microbiota-gut-ubwonko. Iyo microbiota yo mu nda ihungabanye, irashobora gutera indwara zitandukanye zo guhindagurika muri sisitemu y'imitsi, nk'indwara ya Alzheimer. Ubusumbane muri microbiota yo mu nda burashobora gutera imitekerereze ya nervice yo hagati hamwe no gutwika karande, bigatuma habaho poroteyine nini itera indwara ya Alzheimer izwi nka beta-amyloide (Aβ). Imisemburo ya Neurotransmitter hamwe na stress ya okiside irashobora kongera ubukana bwindwara ya Alzheimer.
Niba iyi hypothesis yemejwe, intego zishobora gukumira no kuvura indwara ya Alzheimer zishobora kuba zirimo prebiotics, probiotics, transplant fecal transplantation, antibiotique, hamwe nuburyo bwihariye bwo kurya. Gutera microbiota ivura igamije kuvugurura microbiota yo munda ikora kuri microbiota-gut-ubwonko. Ubu buryo bugamije kugabanya umusaruro udasanzwe wa metabolike, kugabanya ubwinjiriro bw’ingirabuzimafatizo z’umubiri zinjira mu bwonko, kugabanya ubwonko bw’imitsi, bityo rero, bikabuza kwegeranya kwa Aβ, bigatera kwegeranya ibyapa bya Aβ. Gutera microbiota rero, bigira uruhare runini mugukemura indwara ya Alzheimer.