Umuti

Uburyo bushya bwo kuvura ingirabuzimafatizo

Uburyo bushya bwo kuvura ingirabuzimafatizo

Mesenchymal stem selile (MSCs) ibaho mubice bitandukanye. Mu 1991, CAPLAN yise itsinda ry'utugingo ngengabuzima dushobora gukurikiza isahani y’umuco wa plastike mu magufa, ikwirakwizwa cyane muri vitro, kandi ikagaragaza itandukaniro ryinshi nka selile stem mesenchymal. MSCs ni ubwoko bwingirabuzimafatizo zikuze zikomoka kuri mesoderm. Mu ikubitiro bitandukanijwe n'amagufa, byaje kuboneka mubice bitandukanye nk'imitsi ya skeletale, tipusi ya adipose, igufwa ryamagufa, ururenda rwamaraso, amaraso yumugozi, amenyo yamenyo, amniotic membrane, na plasita.

Ingirabuzimafatizo ya Neuronal Mesenchymal ni ingirabuzimafatizo zikuze zifite imbaraga zo kwiyubaka no gutandukanya imbaraga nyinshi, zishobora gutandukanya ibice bitandukanye ningingo zikomoka kuri mesoderm. Mugihe itandukaniro ryibanze ryabo ririmo tissue nuduce twingingo zikomoka kuri mesoderm, ubushakashatsi bwerekanye kandi ubushobozi bwa MSCs bwo gutandukanya hepatocytes, neuron, na selile epithelia, nibindi, bitajyanye na mesoderm.

Twandikire

MSCs

Porogaramu ya mesenchymal stem selile (MSCs) ikubiyemo ibice bikurikira:

Indwara za Autoimmune:Sisitemu ya lupus erythematosus, rubagimpande ya rubagimpande.

Uburyo bwo kubaga:Gukomeretsa umugongo, necrosis avascular yumutwe wigitsina gore, osteoarthritis, nibindi.

Kurwanya gusaza no kwisiga:Kuvugurura byuzuye hejuru yuruhu, kugumana ubuzima bwumusore.

Indwara ya Endocrine Sisitemu:Diyabete, ibibazo bya diyabete, nibindi

Indwara z'umutima n'imitsi:Indwara ya Myocardial, indwara z'umutima, umutima wagutse, n'ibindi.

Indwara ya Hematologiya:Gutezimbere imikorere ya hematopoietic gukira, kwanga kurwanya immunite, nibindi.

Indwara zifata imitsi:Indwara y'ubwonko, indwara ya Parkinson, urukurikirane rw'imitsi, n'ibindi.

Indwara zo munda:Cirrhose, colitis ibisebe, nibindi

Ingirabuzimafatizo

Ingirabuzimafatizo ngengabuzima ni ubwoko bwihariye bwa selile ifite ubushobozi budasanzwe nubushobozi bwo gutandukanya ubwoko butandukanye bwa neuron na selile neuroglial. Zibaho muri sisitemu yumuntu, harimo ubwonko, uruti rwumugongo, nizindi ngingo zifata imitsi.

Ingirabuzimafatizo ngengabuzima zifite ubushobozi bwo kwiyubaka, guhora zigabana kubyara ingirabuzimafatizo nshya. Bafite kandi ubushobozi bwo gutandukanya ubwoko butandukanye bwingirabuzimafatizo, nka neuron, astrocytes, na oligodendrocytes.

Zifite uruhare runini mugutezimbere no kubungabunga sisitemu yimitsi, ifasha mugusana ingirabuzimafatizo zangiritse no gukomeza imikorere isanzwe.

Uturemangingo ngengabuzima twa neural bemeza ko dushobora kuvura indwara zimwe na zimwe z’imitsi n’imvune, urugero nk'indwara ya Parkinson, ibikomere by'umugongo, n'indwara zimwe na zimwe zifata ubwonko. Ubu bushobozi bwashimishije abantu benshi mubushakashatsi bwubuvuzi.

NK

Utugingo ngengabuzima twa NK, tuzwi kandi ku ngirabuzimafatizo ya Killer, ni lymphocytes nini ya granular ikomoka ku magufa. Bagize 5% -10% ya lymphocytes zose mumaraso ya peripheri. Utugingo ngengabuzima ni ingirabuzimafatizo zikomeye zishobora kubuza gutera bagiteri na virusi, kurandura kanseri, indwara, ndetse no gusaza. Bafite ingaruka zidasanzwe mu gukumira kanseri no gutinda gusaza kw'ibinyabuzima kandi bizwi n’ubuvuzi nk '"umurongo wa mbere wo kwirwanaho" mu mubiri ndetse n "" abashinzwe umutekano "mu maraso.

Ibiranga Utugari twa NK

Ubwunganizi:Kurandura bagiteri zitandukanye / virusi no gukuraho ingirabuzimafatizo / kanseri.
Igihagararo:Kuraho ingirabuzimafatizo no gusaza metabolism isanzwe.
Guhagarara no gukomera kwingirabuzimafatizo za NK bigira ingaruka kuburyo butaziguye mubushobozi bwumubiri bwo kurwanya indwara. Nk’uko OMS ibigaragaza, amabuye ane y'ifatizo mu kongera imbaraga z'umubiri ni: 70% imirire + 10% imitekerereze + 10% imyitozo + 10% ikiruhuko. Byongeye kandi, kuzuza selile NK hamwe nizindi selile zumubiri birashobora gukangura no kongera imikorere yumubiri wumubiri, kugera kuntego zo gukumira no kuvura.

Ingaruka zo Kurwanya Gusaza Ingirabuzimafatizo za NK

Kurandura burundu ingirabuzimafatizo zishaje, gushiraho inzitizi ikomeye yumubiri.

Kuzuza ingirabuzimafatizo nshya, gutinda gusaza kw'ingingo.

Kwiyongera icyarimwe imbaraga zindi mikorere yumubiri mugihe uhindura umubiri.

Kurwanya selile zanduye virusi, kwirinda no kugabanya indwara zifata umutima, endocrine, umwijima, impyiko, nindwara zifata imitsi.

Gutezimbere indwara zidakira zijyanye n'ubudahangarwa nka gout, hepatite, nibindi.

Gutezimbere kwibuka nibikorwa byo kumenya.

Kugabanya umunaniro, kongera imbaraga no gukomera.

Kugabanuka mumaganya ya psychologiya, gusinzira neza, no kuringaniza amarangamutima.

UKO BYINSHI

Ubuvuzi bwa CIK ni uburyo bwo kuvura ingirabuzimafatizo zongera imbaraga kandi zigakora ingirabuzimafatizo z'umubiri z'umurwayi, nka selile Cytokine-Induced Killer, kugira ngo zongere ubushobozi bwo kwica selile. Ingirabuzimafatizo za CIK ziboneka muguhindura ingirabuzimafatizo ziva mumaraso ya periferique yumurwayi, hanyuma igasubizwa mumubiri wumurwayi.

Ahantu ho gukoreshwa: Ubuvuzi bwa CIK bukoreshwa cyane mu kuvura kanseri, cyane cyane ku barwayi ba kanseri yo mu rwego rwo hejuru nka kanseri y'ibihaha, kanseri y'ibere, kanseri yo mu gifu, kanseri y'umwijima, n'ibindi. Igikorwa cyayo ni ukongera imbaraga z'umubiri mu kurwanya no kurandura kanseri ya kanseri , bityo kunoza ibisubizo byubuvuzi nigipimo cyo kubaho.

PRP

PRP nikintu gikungahaye kuri platel gikurwa mumaraso yumurwayi ukoresheje tekinoroji nka centrifugation. Ikungahaye ku bintu bikura na poroteyine zitera gusana ingirabuzima fatizo, kuvugurura, gukira ibikomere, no gusana imyenda yoroshye. PRP isanzwe ikoreshwa mubuvuzi kugirango iteze imbere gukira ibikomere, gukira kuvunika, no kubaga amavuta yo kwisiga.

Igipimo cyo gusaba: PRP ikoreshwa cyane cyane muri orthopedie, kubaga plastique, kuvura amenyo, mubindi bice. Ikoreshwa mu kuvura ibikomere by'imitsi, tendonitis, ibikomere bya karitsiye, ibikomere bidakira, bifasha mu kunoza ibisubizo by’ubuvuzi no kwihutisha gukira.