Chirongwa chekurapa checerebellar atrophy

1.Genetic:
Spinocerebellar ataxia (SCA).
Friedreich's ataxia.
Dentatorubral-pallidoluysian atrophy (DRPLA).

2.Degenerative:
Multiple system atrophy mhando C (MSA-C).

3.Ischemic-Hypoxic:
Carbon monoxide poisoning.

4.Drug toxicity:
Phenobarbital sodium.

5.Kuzvimba:
Sequelae yeacute cerebelitis.

6. Alcohol toxicity:
Doro cerebellar degeneration.

7. Zvimwe:
Paraneoplastic cerebellar degeneration.

1.Ataxia: Ataxia ndiyo inonyanya kuratidzwa kwekliniki yecerebellar atrophy. Varwere vanoratidza kusagadzikana pavanenge vakamira, vachizununguka, uye vachinetseka kuchengetedza chiyero, kazhinji vasingakwanisi kumira negumbo rimwe. Mafambiro avo haana kugadzikana, ane nhanho dzakafara-dzika, kuzunguzika kwedivi, uye makumbo nemaoko ekumusoro akatambanudzwa achitambanudzwa sekunge ari kuda kudonha. Hadzina kurongeka zvakanaka, uye mafambiro anowanzopfuura pane chinangwa, uye manyorero anogona kunge asina kugadzikana uye asina kujairika, aine mavara akakura zvishoma nezvishoma.

2. Cerebellar Dysarthria: Kutaura kunononoka, kune slurred, monotone, uye toni dzemhino, dzinofanana nemaitiro ekuimba. Izvi zvinokonzerwa nekushaikwa kwekubatana mumhasuru dzekutaura dzakadai semiromo, rurimi, uye pharynx.

3. Ocular Motor Disorders: Pakutanga mu cerebellar atrophy, varwere vanogona kuona disconjugate kutarisa uye oculomotor dysfunction. Vanogona kunge vaine kudengenyeka kwakakomba mumaziso, nezviitiko zvishoma zvinoratidza kuderera kana rebound nystagmus.

4.Hypotonia: Hypotonia inonyanya kucherechedzwa muacute cerebellar hemisphere maronda uye haawanzowaniki mumaronda asingaperi. Nekudaro, mune zvimwe zviitiko zvecerebellar atrophy, panogona kuve nekufambira mberi kwemhasuru hypertonia, yakafanana nekudedera-kunyanya kuoma mitezo.

5.Non-Motor Manifestations: Izvi zvinosanganisira kukanganisa kwekuziva uye mutauro. Humwe humbowo hunoratidza kuwirirana pakati pecerebellum uye kusagadzikana kwepfungwa senge schizophrenia, bipolar disorder, uye kupindwa muropa maitiro.

1.Neurological Examination:

(1) Muedzo weFinger-to-Nose: Raira murwere kuti awedzere uye abvute nhengo yepamusoro, bata mhino yavo nemunwe, uye dzokorora chiito chacho nenzira dzakasiyana uye nekumhanya, nemaziso akazaruka uye akavhara, achienzanisa mativi ose maviri. Ataxia inoratidzwa nekumhanya kusingaenderane uye kurongeka, kukanganisa, kana kuda kugadziridzwa kusvika kune chinangwa. Mune cerebellar hemisphere maronda, ataxia inonyanya kutaurwa kune rumwe rutivi sechinangwa chinosvika, kazhinji kukurira chinangwa.

(2) Chitsitsinho-ku-Shin Muedzo: Murwere anorara akafuratira uye anoita zviito zvitatu zvakatevedzana: kusimudza uye kutambanudza imwe nhengo yezasi, kuisa chitsitsinho pane yakatarisana yakatambanudzwa yegumbo rezasi, ipapo kutsvedzerera chitsitsinho pasi peshin, nechinangwa chechokwadi uye. kufamba kwakabatana. Mukukuvadzwa kwecerebellar, kusimudza gumbo uye kubata shin kunogona kusagadzikana nekuda kwekusaona kudzikama kwekuona uye kudengenyeka kwechinangwa kunokonzera kudzika kudzika.

(3) Rapid Alternating Movements Test: Murwere anokurumidza kurova kumashure kweruoko rwakapesana, kana kuti anoita matauriro anokurumidza uye supination mafambiro epamberi, kana kuchinjana kubata tafura nechanza uye kumashure kweruoko. Mukukuvara kwecerebellar, mafambiro haanzwisisike uye ane rhythmically irregular.

(4) Rebound Muedzo: Nemaziso akavharwa, imwe nhengo yepamusoro inokweshwa zvine simba uye yobva yaburitswa nemuongorori. Mumaronda ecerebellar, kusarongeka kwakashata pakati peagonist nemhasuru dzeanopikisa zvinogona kukonzera mafambiro akawandisa zvichikonzera kuzvirova-rova. Neimwe nzira, maoko ese ari maviri anochengetwa pamberi uye akatambanudzwa, uye muongorori anoerekana aasundira pasi obva aburitsa. Vanhuwo zvavo vanogona kudzoka nenzira kwayo kunzvimbo yepakutanga, nepo avo vane cerebellar ataxia vasingakwanisi kudzora kurongeka pakati peagonist neanopikisa tsandanyama, kazhinji zvichikonzera kufamba kwakanyanya uye kutenderera kwenguva refu.

(5) Muedzo Wekunongedza Kwapfuura: Murwere anotambanudza ruoko rwepamusoro kumberi, oisa munwe weindekisi pachigunwe chemuongorori chakamira, osimudza ruoko rwakati kwati kwati oudzosa pasi kuti abate chigunwe chemuongorori. Kuongororwa kunoitwa nemurwere achichengetedza nhengo yepamusoro yakatambanudzwa, kutanga nemaziso akazaruka uye akazovhara. Mukukuvadzwa kwecerebellar, chigunwe chemurwere hachinongedze pamunwe wemuongorori asi chinodarika.

(6) Sit-Up Test: Murwere anorara akatsikitsira, maoko akaiswa pachipfuva pasina anomutsigira, uye anoedza kugara. Muvanhuwo zvavo, hunde chete ndiyo inotambanuka, uye makumbo ese ezasi anogona kuora mwoyo pasina kusiya mubhedha. Mune varwere vane cerebellar kukuvadzwa, zvese muhudyu uye hunde flex panguva imwe chete, uye ese ari maviri makumbo ezasi anosimudza, anonzi sechiratidzo chekubatana.

2.Neuroimaging:

CT uye magnetic resonance imaging (MRI) inogona kuratidza cerebellar atrophy, inoratidzirwa nekuwedzera uye kuwedzera cerebellar fissures, kuderedzwa kwezwi, kutaridzika kwemashizha emashizha, matsime e cerebellar akawedzera, uye kuwedzera kwechina ventricle.

Kuongorora cerebellar atrophy hakuwanzo kuoma uye kunowanzoenderana nenhoroondo yekurapa kwemurwere, zviratidzo, kuongororwa kwekiriniki, uye zvidzidzo zvekufungidzira.