Ukwelashwa

Indlela yokwelapha ye-Stem Cell emisha

Amaseli we-Mesenchymal stem (MSCs) akhona kumathishu ahlukahlukene. Ngo-1991, i-CAPLAN yaqamba iqembu lamaseli akwazi ukunamathela kumapuleti amasiko epulasitiki emnkantsheni, abe nokwanda okuphezulu kwe-vitro, futhi abonisa ukuhlukaniswa okunamandla njengamaseli e-mesenchymal stem. Ama-MSC awuhlobo lwamaseli esiqu esidala anamandla amaningi asuka ku-mesoderm. Ekuqaleni behlukanisiwe nomnkantsha, kamuva batholakala ezicutshini ezihlukahlukene ezifana nezicubu zamathambo, izicubu ze-adipose, umnkantsha, umnkaba, igazi lentambo, izicubu zamazinyo, i-amniotic membrane, ne-placenta.

I-Neuronal Mesenchymal Stem Cells amaseli e-stem amadala anamandla okuzivuselela kanye namandla amaningi okuhlukanisa, akwazi ukuhlukana abe izicubu nezitho ezihlukahlukene ezitholakala ku-mesoderm. Nakuba ukuhlukaniswa kwawo okuyinhloko kuhilela izicubu nezitho zomzimba ezivela ku-mesoderm, ucwaningo luye lwabonisa amandla e-MSC okuhlukanisa abe ama-hepatocyte, ama-neurons, namaseli e-epithelial, phakathi kokunye, angahlobene ne-mesoderm.

Xhumana nathi

Ama-MSC

Ukusetshenziswa kwe-mesenchymal stem cell (MSCs) kuhlanganisa lezi zindawo ezilandelayo:

Izifo zesistimu ye-Autoimmune:I-Systemic lupus erythematosus, i-rheumatoid arthritis.

Izimo Zokuhlinza:Ukulimala komgogodla, i-avascular necrosis yekhanda lesifazane, i-osteoarthritis, njll.

I-Anti-Aging ne-Cosmetic:Ukuvuselela ngokugcwele ubuso besikhumba, ukugcina izimo zomzimba wobusha.

Izifo zesistimu ye-Endocrine:Isifo sikashukela, izinkinga zesifo sikashukela, njll.

Izifo zenhliziyo:I-myocardial infarction, isifo senhliziyo, i-dilated cardiomyopathy, njll.

Izinkinga ze-Hematological:Ukukhuthaza ukutholwa komsebenzi we-hematopoietic, ukwenqatshwa kwe-anti-immune, njll.

I-Neurological Disorders:I-Cerebral palsy, isifo sikaParkinson, i-sequelae ye-stroke, njll.

Izifo Zamathumbu:I-Cirrhosis, i-ulcerative colitis, njll.

Amaseli E-Neural Stem

Amaseli we-Neural stem awuhlobo olukhethekile lweseli elinamakhono ahlukile namandla okuhlukanisa abe izinhlobo ezahlukahlukene zama-neurons namaseli e-neuroglial. Zikhona ohlelweni lwezinzwa lomuntu, okuhlanganisa ubuchopho, umgogodla, nezinye izicubu zemizwa.

Amaseli e-Neural stem anekhono lokuzivuselela, ahlukane ngokuqhubekayo ukuze akhiqize amaseli amasha. Futhi banamandla okuhlukanisa abe izinhlobo ezahlukahlukene zamaseli e-neural, njengama-neurons, ama-astrocyte, nama-oligodendrocyte.

Zidlala indima ebalulekile ekuthuthukisweni nasekugcinweni kwesimiso sezinzwa, zisiza ekulungiseni izicubu zemizwa ezilimele nokugcina ukusebenza kwemizwa evamile.

Amaseli e-Neural stem kukholakala ukuthi anezinhlelo zokwelapha ezingaba khona ezimweni ezithile zemizwa nokulimala, njengesifo sika-Parkinson, ukulimala komgogodla, kanye nezifo ezithile ze-neurodegenerative. Leli khono lidonse ukunaka okubanzi ocwaningweni lwezokwelapha.

njll

Amaseli e-NK, aziwa nangokuthi ama-Natural Killer Cells, angama-lymphocyte amakhulu ayimbudumbudu asuka emnkantsheni. Bakha u-5% -10% wengqikithi yama-lymphocyte egazini le-peripheral. Lawa maseli angamaseli omzimba abalulekile angavimbela ukuhlasela kwebhaktheriya kanye negciwane, aqede amangqamuzana anomdlavuza, ama-pathological, kanye nokuguga. Banemiphumela eyingqayizivele ekuvimbeleni umdlavuza nokubambezeleka kokuguga futhi babonwa umphakathi wezokwelapha "njengomugqa wokuqala wokuzivikela" emzimbeni kanye "nabahlanzi" begazi.

Izimpawu zamaseli e-NK

Ukuzivikela:Ukuqeda amagciwane/amagciwane ahlukahlukene ahlaselayo kanye nokususa amaseli e-pathological/cancer.
Ukuzinza:Ukukhipha amangqamuzana asebekhulile kanye nokuzinzisa imetabolism evamile.
Ukuzinza nobungqabavu bamaseli e-NK kuthinta ngqo ikhono lomzimba lokulwa nezifo. Ngokusho kwe-WHO, izisekelo ezine zokuvuselela amasosha omzimba yilezi: 70% umsoco + 10% isimo sengqondo + 10% ukuzivocavoca + 10% ukuphumula. Ukwengeza, ukugcwalisa amaseli e-NK namanye amaseli omzimba angavuselela futhi athuthukise ukusebenza komzimba wokuzivikela komzimba, kufinyelele imigomo yokuvimbela nokwelashwa.

I-Anti-Aging Effects yamaseli e-NK

Ukuqedwa okuqondile kwamangqamuzana aguga, ukusungula umgoqo oqinile wokuzivikela komzimba.

Ukwengezwa kwamaseli amasha anamandla, kunciphisa ukuguga kwesitho.

Ukuthuthukiswa kanyekanye kweminye imisebenzi yamangqamuzana omzimba omzimba ngenkathi kuthuthukisa umzimba.

Ukulwa namaseli atheleleke ngegciwane, ukuvimbela nokunciphisa izifo zenhliziyo, i-endocrine, isibindi, izinso, nesistimu yezinzwa.

Ukuthuthukiswa kwezifo ezingapheli ezihlobene nokuzivikela komzimba njenge-gout, i-hepatitis, njll.

Ukuthuthukisa inkumbulo nokusebenza kwengqondo.

Ukunciphisa ukukhathala, ukwanda kwamandla namandla.

Ukuncipha kokukhathazeka okungokwengqondo, ukulala okuthuthukisiwe, nokulinganisela ngokomzwelo.

MALINI

Ukwelashwa kwe-CIK kuyindlela yokwelashwa kwamangqamuzana omzimba ethuthukisa futhi yenze amasosha omzimba esiguli asebenze, njengamaseli e-Cytokine-Induced Killer, ukuze akhulise amandla awo okubulala amaseli wesimila. Amaseli e-CIK atholwa ngokuhlakulela amangqamuzana egazini lesiguli eliseceleni, aphinde afakwe emzimbeni wesiguli.

Ububanzi bokusebenza: Ukwelashwa kwe-CIK kuvame ukusetshenziswa ekwelapheni umdlavuza, ikakhulukazi ezigulini ezinomdlavuza ezisezingeni eliphezulu njengomdlavuza wamaphaphu, umdlavuza webele, umdlavuza wesisu, umdlavuza wesibindi, njll. Umsebenzi wawo uwukuthuthukisa amasosha omzimba ukulwa nokuqeda amangqamuzana omdlavuza. , ngaleyo ndlela kuthuthukiswe imiphumela yokwelashwa namazinga okusinda.

I-PRP

I-PRP iwuketshezi olunothiswe ngeplatelet ekhishwa egazini lesiguli kusetshenziswa amasu afana ne-centrifugation. Icebile ezicini zokukhula kanye namaprotheni akhuthaza ukulungiswa kwezicubu, ukuvuselelwa, ukuphulukiswa kwamanxeba, nokulungiswa kwezicubu ezithambile. I-PRP ivame ukusetshenziswa kwezokwelapha ukukhuthaza ukuphulukiswa kwesilonda, ukuphulukiswa kokuphuka, kanye nokuhlinzwa kwezimonyo.

Ububanzi besicelo: I-PRP isetshenziswa ngokuyinhloko ku-orthopedics, ukuhlinzwa kwepulasitiki, amazinyo, phakathi kweminye imikhakha. Isetshenziselwa ukwelapha ukulimala kwe-musculoskeletal, i-tendonitis, ukulimala kwe-cartilage, amanxeba angapheli, ukusiza ekuthuthukiseni imiphumela yokwelashwa nokusheshisa ukululama.