Yunivesite ya Harvard potsiriza yawulula mgwirizano pakati pa khofi ndi thanzi-kudandaula posadziwa kale!

Khofi wakhala chakumwa chofunikira kuti anthu ambiri akhale tcheru komanso amphamvu. Kwa akatswiri amakono, tinganene kuti mphamvu zawo zapakati pa sabata zimachokera ku khofi. Kaya ndi chifukwa chokhala maso kapena kungosangalala ndi kapu yomwe ili m'manja, khofi wachoka pakukhala chakumwa chambiri mpaka kukhala gawo la moyo wa anthu ambiri, ndikulowa m'moyo wamakono.

Koma zomwe simungadziwe ndikuti khofi ili ndi phindu linanso lodabwitsa, lowululidwa posachedwa ndi asayansi aku Harvard University ...

Maphunziro angapo, kuphatikiza omwe akuchokera ku Harvard University ndi mabungwe ena ofufuza, awonetsa kuti khofi ili ndi zabwino zambiri. Ikhoza kuchepetsa chiopsezo cha khansa zosiyanasiyana, kulepheretsa kukula kwa chotupa, kuchepetsa chiopsezo cha imfa zonse, kuchepetsa chiopsezo cha matenda a Alzheimer's ndi Parkinson, kuchepetsa chiopsezo cha matenda a mtima, kumathandiza kuti thupi likhale lolemera bwino, ndi kuchepetsa chiopsezo cha ndulu; mwa zina zabwino.

Zopindulitsa zambiri za khofi zimagwirizana kwambiri ndi mazana a mankhwala omwe amadziwika pang'ono omwe amapezeka mu nyemba za khofi. Mwachitsanzo, khofi imakhala ndi caffeine, yomwe ili ndi gwero lamphamvu la antioxidants ndi bioactive mankhwala.

Kumwa khofi kumachepetsa chiopsezo cha khansa ya m'mimba komanso khansa ya chiwindi.

Yunivesite ya Harvard yotchuka padziko lonse inavumbula ubwino wa thanzi la khofi-kumwa khofi kungachepetse chiopsezo cha khansa ya colorectal ndi 15%, ndipo kumwa makapu awiri a khofi patsiku kungachepetse mwayi wokhala ndi khansa ya chiwindi ndi 43%.

Panthawi imodzimodziyo, kafukufuku amene Pulofesa Stephanie L. Schmit ndi ena a ku Norris Comprehensive Cancer Center pa yunivesite ya Southern California mumzinda wa *Cancer Biomarkers and Prevention* wakulitsa chikondi chathu pa khofi—khofi akhoza kuchepetsa chiopsezo cha khansa ya m’mimba. ndi 26%.

Kafukufukuyu ndi kafukufuku wokhudzana ndi kuchuluka kwa anthu odwala khansa yapakhungu yomwe inachitika kumpoto kwa Israel. Ofufuzawa adapanga mafunso ovomerezeka, owerengeka omwe amamwa khofi pafupipafupi kwa odwala 5,145 omwe ali ndi khansa ya colorectal komanso anthu 4,097 athanzi omwe alibe mbiri ya khansa yapakhungu.

Detayo idawulula kuti mutatha kusintha zomwe zimadziwika pachiwopsezo, kumwa khofi pang'ono (kapu imodzi mpaka 2 patsiku) kumatha kuchepetsa chiopsezo chokhala ndi khansa yapakhungu ndi 26%. Kuonjezera apo, pamene kumwa khofi kumawonjezeka, chiopsezo chokhala ndi khansa ya colorectal imachepa pang'onopang'ono, zomwe zimawonekera kwa khansa ya m'matumbo ndi rectum.

Kuphatikiza apo, ofufuza a Dana-Farber Cancer Institute adafalitsa kafukufuku mu *Journal of Clinical Oncology* kunena kuti kumwa khofi pafupipafupi kumatha kuchepetsa kuyambiranso kwa chotupa ndikuwonjezera kupulumuka kwa odwala omwe ali ndi khansa yamtundu wa III.

Kafukufukuyu adatsata zakudya za odwala 953 omwe ali ndi khansa ya colorectal omwe amalandila chemotherapy kwa miyezi isanu ndi umodzi. Iwo adapeza kuti odwala omwe amamwa makapu anayi kapena kuposerapo a khofi patsiku (omwe ali ndi caffeine pafupifupi mamiligalamu 460) anali ndi chiopsezo chochepa cha 42% cha kuyambiranso kwa khansa poyerekeza ndi omwe sanamwe khofi. Panthawi yotsatila, odwala omwe amamwa makapu anayi kapena kuposerapo a khofi anali ndi chiopsezo chochepa cha 33% cha kufa ndi khansa kapena chifukwa china chilichonse poyerekeza ndi osamwa khofi.

Kufufuza kwina kunasonyeza kuti kuchepetsedwa kwa chiwopsezo cha khansa kunabwera chifukwa cha caffeine yomwe imatengedwa ndi odwala, osati kuchuluka kwa zigawo zina za khofi.

Zotsatira za insulin zitha kusinthidwa ndi khofi mtsogolo.

Matenda a shuga ndi omwe afala kwambiri padziko lonse lapansi, ndipo odwala matenda ashuga opitilira 380 miliyoni padziko lonse lapansi. Chaka chilichonse, anthu pafupifupi 80,000 amamwalira ndi matenda a mtima komanso mavuto ena okhudzana ndi matenda a shuga.

Kwa odwala omwe ali ndi matenda amtundu woyamba komanso amtundu wa 2, kubaya insulin ndi gawo lofunikira pa moyo wawo watsiku ndi tsiku. Komabe, ngakhale jakisoni wa insulin ndi njira yabwino yothandizira, siangwiro. jakisoni wa insulin watsiku ndi tsiku siwovuta komanso wosavuta kuyiwala.

Magulu ofufuza apeza kuti mtundu wa selo la impso ukhoza kupanga insulini ukazindikira kuti caffeine m'magazi. Pambuyo pake, adayesanso mbewa khumi za matenda a shuga, ndipo mbewa zikadya khofi, kuthekera kwawo kuwongolera kuchuluka kwa shuga m'magazi kunali kwabwinoko kuposa mbewa zabwinobwino!

Gulu lofufuzalo lidati ma cell a impso ofanana amapezeka m'thupi la munthu, ndipo njira yeniyeni yopangira insulini ikufunikabe kufufuzidwa.

Ndipotu, zotsatira zoyeserazi sizopanda maziko. Kafukufuku wopangidwa ndi University of Harvard okhudza anthu 126,000 adawonetsa kuti anthu omwe amamwa khofi nthawi zonse amakhala ndi chiopsezo chochepa chokhala ndi matenda a shuga amtundu wachiwiri.

Kafukufukuyu wabweretsa chiyembekezo kwa odwala ambiri a shuga; mwina m'tsogolomu, odwala matenda a shuga adzatha kusangalala ndi kapu ya khofi kuti alimbikitse kupanga insulini, kuthetsa kufunikira kwa jakisoni wowonjezera!

**Khofi Atha Kulepheretsa Kukula kwa Khansa ya M'mawere**

Ofufuza pa chipatala cha Skåne University ku Lund University ku UK adafalitsa zomwe adapeza mu *Clinical Cancer Research*, zomwe zikuwonetsa kuti kwa amayi omwe ali ndi khansa ya m'mawere omwe akulandira chithandizo cha tamoxifen, kumwa khofi kumatha kulepheretsa kukula kwa chotupa komanso kuchepetsa chiopsezo choyambiranso.

Kafukufukuyu adayang'ana odwala 1,090 ku Sweden omwe adapezeka ndi khansa ya m'mawere yowopsa, makamaka kuwunika mgwirizano pakati pa zinthu ziwiri zomwe zimapezeka mu khofi waku Sweden - caffeine ndi caffeic acid - komanso mawonekedwe a chotupa komanso kupulumuka kopanda matenda.

Zotsatira zinasonyeza kuti mwa amayi osachepera 500 omwe amamwa mankhwala a tamoxifen, omwe amamwa makapu awiri a khofi patsiku anali ndi chiopsezo choyambiranso khansa ya m'mawere yomwe inali theka la amayi omwe amamwa makapu awiri kapena ochepa, kapena osamwa khofi nkomwe. . Kuphatikiza apo, azimayiwa anali ndi zotupa zazing'ono komanso kuchepa kwa zotupa zomwe zimadalira mahomoni.

Ofufuza akukhulupirira kuti caffeine ndi caffeic acid zimatha kupangitsa kuti maselo asamayende bwino komanso kufa kwa maselo, potero kumalimbitsa zotsatira za mankhwala a tamoxifen.

Khofi ndi wathanzi, koma cholinga chake si kuwonjezera shuga.

Ndikofunika kuzindikira kuti si khofi yonse yomwe ili ndi thanzi; khofi yemwe akutchulidwa m'nkhaniyi ndi khofi wakuda wakuda wopanda zowonjezera.

Pakadali pano, ma khofi ambiri apompopompo kapena khofi wokometsedwa pamsika ali ndi shuga wambiri woyera komanso zotsekemera zopanda mkaka, zomwe zimawapangitsa kukhala opanda thanzi. Kuonjezera apo, "zakumwa za caffeine" zomwe zimakhala ndi milu ya zonona zotsekemera komanso zotsekemera kwambiri (kuphatikizapo tiyi wamkaka) sizimangokhala ndi zopatsa mphamvu zambiri komanso zimatha kuyambitsa matenda osiyanasiyana chifukwa cha shuga wambiri, choncho ndi bwino kuzidya mochepa.

Ngati mupeza khofi wakuda wowawa kwambiri, mukhoza kuwonjezera mkaka pang'ono kapena ufa wa mkaka.

Ndikoyeneranso kutchula kuti ngakhale pakali pano palibe kuletsa kwa amayi apakati kumwa khofi, komanso kumwa mowa wa khofi tsiku lililonse sikuposa mamiligalamu 200, kafukufuku pamutuwu akadali wosatsimikizika. Choncho, ndi bwino kuchepetsa kumwa khofi pa nthawi ya mimba.

Chidule

Pa chithandizo cha khansa, madokotala ndi odwala amawunika mosalekeza momwe matenda akupitira patsogolo ndikufufuza mwachangu njira zothandizira kuti apulumuke. Mochulukirachulukira, kafukufuku wowonetsa kuti, kuphatikiza pa njira zachikhalidwe monga opaleshoni, radiotherapy, ndi chemotherapy, kuphatikiza immunotherapy kungathandize kubwezeretsa magwiridwe antchito a thupi, kuchepetsa kuyambiranso, komanso kupewa metastasis.

Zoonadi, chithandizo cha sayansi ndi chodziŵika chopatsa thanzi chingathandize kuchepetsa zizindikiro, kulimbitsa thupi, kuchepetsa cachexia, kukulitsa moyo, ndiponso kuchirikiza kuchira kwa khansa.

Kuphatikiza pa kulandira chithandizo, odwala khansa akuyeneranso kukulitsa kumvetsetsa kwawo za chithandizo ndi kuchira kudzera m'maphunziro, kulumikizana momasuka ndi madotolo awo, ndikupeza njira yothandiza yochira yomwe ingawathandize. Mothandizidwa ndi kusintha kwazakudya komanso njira zolimbikitsira ma cell, amatha kuyesetsa kubwerera kumoyo wathanzi posachedwa!